Gabriel Vilardi and Kyle Connor also scored for Winnipeg, and Connor Hellebuyck made 28 saves. The Jets’ losing streak was their longest this season, and Winnipeg is 4-7-0 after starting the season 15-1-0.
Tage Thompson and Dylan Cozens scored for the Sabres, who are winless in their past five games (0-3-2). Ukko-Pekka Luukkonen also made 28 saves.
Lowry’s winning goal came on a rebound from defenseman Josh Morrissey’s shot that slid to the left of Luukkonen in the crease.
Sabres head coach Lindy Ruff became the fourth coach to reach the 1,800-game mark behind the bench joining Barry Trotz, Paul Maurice and Scotty Bowman.
Jets: This was the third time in the past seven games the Jets scored more than one goal, and they’ve won two of those games.
Sabres: Thompson’s power-play goal in the first period ended a run of 16 consecutive power plays without a goal. The most recent one before that came Nov. 20 in Los Angeles from Jason Zucker.
An apparent goal by Sabres rookie Tyson Kozak at 2:24 of the third period was overturned after a goalie interference challenge by Jets coach Scott Arniel. Replay determined Sabres forward Beck Malenstyn impeded Hellebuyck’s attempt to make a save.
The Sabres five-game winless streak is their longest since they lost eight straight games (0-8-0) from Nov. 4-19, 2022.
The Sabres’ five-game homestand continues Saturday against Utah, while the Jets will face the Blackhawks in Chicago on Saturday.